The opening-night schedule begins with a rematch of last year's final as the RMM Gonzaga Vikings taking on the defending champions OMT Shamrocks.
That will be followed by a game between the Rona Storm and the Knights, the league's two Mount Pearl-based teams.
The Fifth Ticket Feildians and Holy Cross Trinity Crusaders, the league's other two teams, will square off at St. Pat's Friday night.